2-Methyl Butyric Acid | Aroma/Fragrance Compound

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General Information

  • Chemical Name: 2-Methyl Butyric Acid
  • Chemical Formula: C₅H₁₀O₂
  • CAS Number: 116-53-0
  • EC Number: 204-141-0
  • Molecular Weight: 102.13 g/mol
  • IUPAC Name: 2-Methylbutanoic Acid

Physical Properties

  • Appearance: Clear, colorless to pale yellow liquid
  • Odor: Strong, sour, and rancid odor
  • Density: 0.937 g/cm³ at 20°C
  • Boiling Point: 178–182°C
  • Melting Point: -5°C
  • Flash Point: 72°C (closed cup)
  • Refractive Index (nD20): 1.415–1.418
  • Vapor Pressure: 0.68 mmHg at 25°C
  • Solubility:
    • Slightly soluble in water
    • Soluble in ethanol, ether, and most organic solvents

Chemical Properties

  • Purity: ≥99% (by GC analysis)
  • Water Content: ≤0.3% (by Karl Fischer Titration)
  • Acidity (as CH₃CH₂COOH): ≥95%
  • Impurities: ≤0.5% (total)

Description

2-Methyl Butyric Acid is a high-purity, industrial-grade carboxylic acid with a distinctive pungent odor. Known for its versatility, it is widely used in the flavor and fragrance industry, as a chemical intermediate, and in various industrial applications. Its unique chemical properties make it an essential ingredient in multiple formulations.

Applications of 2-Methyl Butyric Acid


Flavor and Fragrance Industry

  • Flavoring Agent:
    • Used to create fruity, buttery, and cheesy flavors for food and beverage products.
    • Commonly employed in dairy flavor formulations, including butter, cheese, and yogurt.
  • Fragrance Ingredient:
    • Key component in perfumes and fragrances for its fruity and creamy aroma.
    • Used in creating esters for natural and artificial scents.

Chemical Intermediate

  • Ester Synthesis:
    • Used in the production of esters like methyl or ethyl 2-methyl butyrate, which are key ingredients in perfumes and food additives.
  • Specialty Chemicals:
    • Acts as a precursor in the synthesis of lubricants, additives, and other specialty compounds.

Pharmaceutical Applications

  • Active Ingredient Production:
    • Used as an intermediate in the synthesis of pharmaceutical compounds.
  • Excipient and Additive:
    • Sometimes included in formulations for its solvent properties.

Industrial Applications

  • Lubricants and Plasticizers:
    • Used in the formulation of lubricants and as a plasticizer in polymer processing.
  • pH Adjustment:
    • Functions as a pH regulator in industrial and chemical processes.

Agricultural Industry

  • Pesticide and Herbicide Formulations:
    • Used as a component in certain agrochemical products.

Research and Development

  • Chemical Studies:
    • Widely used in academic and industrial research for studying carboxylic acids and their derivatives.
  • Biochemical Pathways:
    • Investigated for its role in metabolic pathways in biological systems.

Cosmetics and Personal Care

  • Fragrance Additive:
    • Included in cosmetics and personal care products for its odor-enhancing properties.

 

Storage Requirements:

  • Temperature Control:
    • Store in a cool, dry, and well-ventilated area, ideally between 15°C and 25°C.
    • Protect from freezing and excessive heat.
  • Container Specifications:
    • Use tightly sealed, corrosion-resistant containers such as stainless steel or HDPE drums.
    • Ensure containers are properly labeled and compatible with acidic substances.
  • Segregation:
    • Keep away from strong oxidizing agents, bases, and reactive metals.
    • Do not store near food, beverages, or feed.
  • Spill Containment:
    • Use secondary containment to prevent accidental release into the environment.

Handling Precautions:

  • Personal Protective Equipment (PPE):
    • Gloves: Acid-resistant gloves (e.g., nitrile or neoprene).
    • Eye Protection: Safety goggles or a full-face shield.
    • Clothing: Long-sleeved clothing or a chemical-resistant apron.
    • Respiratory Protection: If ventilation is inadequate, use a respirator approved for organic vapors.
  • Safe Handling Practices:
    • Avoid direct contact with skin, eyes, and clothing.
    • Do not inhale vapors or mist; ensure adequate ventilation or use local exhaust systems.
    • Transfer materials in a well-ventilated area using appropriate tools to minimize spills.
  • Hygiene Measures:
    • Wash hands thoroughly with soap and water after handling.
    • Remove and wash contaminated clothing before reuse.
  • Emergency Preparedness:
    • Keep an emergency eyewash station and safety shower nearby.
    • Have neutralizing agents (e.g., sodium bicarbonate) readily available for small spills.

Disposal Considerations:

Dispose of 2-Methyl Butyric Acid and its containers in accordance with local, regional, and international regulations. Avoid release into waterways or the environment.

 

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