Skatole (3-Methylindole) – Fragrance & Research

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Chemical Identity:

  • Chemical Name: 3-Methylindole
  • Common Name: Skatole
  • CAS Number: 83-34-1
  • Molecular Formula: C9H9N
  • Molecular Weight: 131.17 g/mol

Physical and Chemical Properties:

  • Appearance: White to pale yellow crystalline solid
  • Odor: Strong, fecal-like odor at high concentrations; floral and musky in diluted forms
  • Melting Point: 95–96°C (203–205°F)
  • Boiling Point: 265°C (509°F)
  • Flash Point: 121°C (250°F)
  • Density: ~1.08 g/cm³
  • Solubility:
    • Soluble in ethanol, ether, and organic solvents
    • Slightly soluble in water

Purity and Grade:

  • Purity: 99% (High Purity Grade)
  • Grade: Laboratory/Reagent Grade

Description

Skatole, or 3-Methylindole, is a naturally occurring organic compound renowned for its dual-purpose functionality in the fragrance and flavor industries, as well as its utility in chemical research. While it exhibits a strong odor in high concentrations, in diluted forms, Skatole provides a sophisticated floral and musky scent commonly utilized in high-end perfumes.

Applications of Skatole (3-Methylindole)

Fragrance Industry

  • Purpose:
    • Skatole is prized for its unique olfactory properties, particularly in diluted forms where it exudes a musky and floral scent.
  • Applications:
    • A key ingredient in luxury perfumes and colognes to enhance musky, floral, or exotic notes.
    • Often used in small quantities to add depth and warmth to fragrance compositions.

Flavor Industry

  • Purpose:
    • In trace amounts, Skatole contributes to complex flavor profiles.
  • Applications:
    • Used in food flavorings to enhance meat or fruit-like flavors.
    • Limited to extremely low concentrations due to its potency; ensure compliance with food safety regulations.

Research and Development

  • Purpose:
    • A valuable compound for chemical research and synthesis.
  • Applications:
    • Studied for its role in biological processes and as a metabolic byproduct in animals.
    • Used in the development of novel synthetic routes for other complex organic compounds.
    • Frequently applied in studies related to odor chemistry and sensory science.

Agricultural and Environmental Research

  • Purpose:
    • Skatole is naturally produced by the breakdown of organic matter and is relevant in agricultural contexts.
  • Applications:
    • Investigated for its role in livestock odor management.
    • Studied in soil and environmental sciences to understand microbial activity and decomposition processes.

Specialty Chemical Formulations

  • Purpose:
    • Serves as an intermediate or additive in specialized chemical formulations.
  • Applications:
    • Incorporated in niche industrial processes requiring specific aromatic characteristics or chemical properties.

Pharmaceutical Research

  • Purpose:
    • Skatole’s biological interactions make it a compound of interest in pharmacology.
  • Applications:
    • Examined for potential effects on human and animal health.
    • Used as a reference compound in metabolic and toxicological studies.

Storage:

  • Temperature: Store at a controlled room temperature, ideally between 15°C and 25°C (59°F to 77°F).
  • Environment: Keep in a cool, dry, and well-ventilated area.
  • Container: Store in a tightly sealed, chemical-resistant container to prevent contamination or loss of potency.
  • Protection from Light: Use opaque or UV-resistant containers to shield the product from light exposure, which can degrade its quality.
  • Segregation: Avoid storing near strong oxidizing agents, acids, or bases to prevent chemical reactions.

Handling:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including gloves, safety goggles, and lab coats, when handling the substance.
  • Ventilation: Use in a well-ventilated area or under a fume hood to prevent inhalation of vapors.
  • Hygiene: Avoid contact with skin, eyes, or clothing. Wash hands thoroughly after handling.
  • Spill Management: In case of a spill, use inert absorbent materials to clean up, and dispose of the waste in accordance with local regulations.
  • Waste Disposal: Dispose of in accordance with federal, state, and local environmental control regulations.

Safety Note:

Refer to the Safety Data Sheet (SDS) for complete safety, handling, and disposal instructions. Keep out of reach of children and untrained individuals.

 

Additional information

Size

5 Grams, 10 Grams

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